The role of Pseudomonas aeruginosa peptidoglycan-associated outer membrane proteins in vesicle formation
نویسندگان
چکیده
Section of Molecular Genetics and Microbiology, Institute for Cellular and Molecular Biology, University of Texas at Austin, Texas, USA Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, University of Texas at Austin, Texas, USA Cellular and Molecular Biology Program, Institute for Cellular and Molecular Biology, University of Texas at Austin, Texas, USA Department of Chemistry and Biochemistry, University of Texas at Austin, Texas, USA
منابع مشابه
Role of Pseudomonas aeruginosa peptidoglycan-associated outer membrane proteins in vesicle formation.
Gram-negative bacteria produce outer membrane vesicles (OMVs) that package and deliver proteins, small molecules, and DNA to prokaryotic and eukaryotic cells. The molecular details of OMV biogenesis have not been fully elucidated, but peptidoglycan-associated outer membrane proteins that tether the outer membrane to the underlying peptidoglycan have been shown to be critical for OMV formation i...
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The Pseudomonas aeruginosa outer membrane was isolated with attached peptidoglycan and fractionated with Triton X-100, ethylenediaminetetraacetate, and lysozyme. The data suggest that major outer membrane proteins F, H2, and I are noncovalently associated with the peptidoglycan.
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متن کاملRoles of the carboxy-terminal half of Pseudomonas aeruginosa major outer membrane protein OprF in cell shape, growth in low-osmolarity medium, and peptidoglycan association.
OprF, the major outer membrane protein of Pseudomonas aeruginosa, is multifunctional in that it can act as a nonspecific porin, plays a role in the maintenance of cell shape, and is required for growth in a low-osmolarity environment. The latter two structural roles of OprF, and OprF's association with the peptidoglycan, have been proposed to be localized in the carboxy terminus of the protein,...
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تاریخ انتشار 2012